Nanosuspension: an emerging nanotechnology for drug delivey system

Shweta Singh, Shweta Jain

Sir Madanlal Institute of Pharmacy, Etawah, Uttar Pradesh, India.

Refer this article

Shweta Singh, Shweta Jain. Nano suspension: an emerging nanotechnology for drug delivey dystem international journal of therapeutic innovation, Nov-Dec 2023, V 1 - I 3, Pages - 0053 – 0063. Doi: https://doi.org/10.55522/ijti.V1I3.0014

ABSTRACT

Now a day’s nanotechnology is one of the advancement technique within the fields of medication. “Nano” way very small in length the particle length starting from 1-a thousand μm. Nano suspensions is particularly developed era within the subject of nano technological know-how. A pharmaceutical nano suspension is described as a totally finely colloid, biphasic, dispersed, solid drug particles in aqueous car, size beneath 1μm, without any matrix cloth, stabilized through surfactants & polymers, prepared through suitable techniques for drug shipping applications, by means of distinctive approaches of routes of administration like oral, topical, parenteral, ocular & pulmonary routes. A nano suspension no longer only solves the troubles of bad solubility and bioavailability, but additionally alters the pharmacokinetics of drug and for that reason improves drug protection and efficacy. Low bioavailability is one of the essential drawbacks associated with capsules which show negative aqueous solubility. The problem is even greater complex for capsules belonging to BCS class II as categorized with the aid of BCS classification system, showing negative solubility. Solubility in each aqueous and nanoqueous media including tablets like carbamazepine, itraconazole and so forth. Nano suspension, is an advancement era overcome those troubles concerning solubility.

Keywords:

Bioavailability, Nanoparticle, Colloidal dispersion, Drug delivery, Nanosuspension, Solubility.